Question

$N{H}_3$ and its derivative do not show nucleophillic addition reactions with aldehydes and ketone in high acidic medium. Justify.

Answer 1

Generally, weak acids are used as catalysts in the addition reaction of aldehydes and ketones with ammonia and its derivatives.

In high acidic medium, ammonia derivative will form their respective salts due to their basic nature and at the same time will lose their nucleophilic nature and hence will not show nucleophilic addition reactions with aldehydes and ketones in high acidic medium.