Law of Conservation of Matter, proven by Lavoisier in 1785: matter can be neither created nor destroyed.
Matter is never destroyed inside of a nuclear reaction, it is simply transferred to a different state. Matter is made from energy at the tiniest, most quantum levels, and the energy gets transferred from one place to another, or from one state to another. When we see a nuclear rection blow something up or "destroy" something, it is actually trasferring that energy elsewhere into different elements.