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Question

Nucleases are found in

A
intestinal juice
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B
large intestine
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C
bile
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D
pancreatic juice
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Solution

The correct option is D pancreatic juice
Nuclease is an enzyme that breaks down the phosphodiester bonds between nucleotides of nucleic acids. Pancreatic juice is secreted by the pancreas that contains various enzymes such as trypsinogen, carboxypeptidases, pancreatic lipases, nucleases, amylases, etc.

Intestinal juice contains a variety of enzymes like disaccharidases (e.g., maltase), dipeptidases, lipases, nucleosidases, etc. The intestinal juice completes the digestion started by pancreatic juice.

The primary function of the large intestine is to store faeces before defaecation and it does not produce any digestive enzyme.

Bile contains bile pigments (bilirubin and biliverdin), bile salts, cholesterol and phospholipids but no enzymes.

Hence, intestinal juice, large intestine and bile do not contain nucleases.

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