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Question

Number of ATP molecules synthesized through substrate level phosphorylation during aerobic respiration of one glucose molecule is:

A
8
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B
6
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C
4
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D
2
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Solution

The correct option is B 6
Substrate-level phosphorylation is a metabolic reaction that results in the formation of ATP or GTP by the direct transfer of a phosphoryl (PO3) group to ADP or GDP from another phosphorylated compound.

Substrate level phosphorylation occurs in the form of glycolysis and Krebs cycle. During glycolysis, substrate level phosphorylation occurs in two steps and as two molecules are involved, it finally produces 4 ATP from a single glucose molecule.
As the molecules move towards Krebs cycle the substrate level phosphorylation occurs in a single step. Due to the presence of two molecules, the ATP produced during Krebs cycle in this manner will be 2 ATP molecules.

Therefore, total ATP molecules obtained from substrate-level phosphorylation​​​​ during aerobic respiration of a glucose​​ molecule​ will be 4+2 = 6 molecules.


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