The correct option is
C Gull's disease
Gull's disease is also known as Myxoedema. It occurs commonly in adults due to hyposecretion of thyroid hormones after the normal physical and mental development of body is complete. The metabolic rate of body becomes low and oxygen consumption by metabolically active tissues gets decreased. There is lack of demand for increased energy by muscles during working or exercise. Legs, feet and ankles get swollen and this condition is known as oedema. Physical and mental processes of the body get slower, hair lose lustre and get brittle and skin becomes coarse.
So, the correct answer is 'Gull's disease'.