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Question

Once released, neurotransmitter molecules typically produce signals in postsynaptic neurons by

A
entering the postsynaptic neuron
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B
attaching to vesicles
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C
binding to presynaptic receptors
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D
binding to postsynaptic receptors
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Solution

The correct option is D binding to postsynaptic receptors
A nerve impulse is transmitted from one neuron to another through junctions called synapses. A synapse is formed by the membranes of a pre-synaptic neuron and a post-synaptic neuron, which may or may not be separated by a gap called synaptic cleft.
Neurotransmitters are involved in the transmission of impulses at these synapses. The axon terminals contain vesicles filled with these neurotransmitters.
When an impulse (action potential) arrives at the axon terminal, it stimulates the movement of the synaptic vesicles towards the membrane where they fuse with the plasma membrane and release their neurotransmitters in the synaptic cleft. The released neurotransmitters bind to their specific receptors, present on the post-synaptic membrane. This binding opens ion channels allowing the entry of ions which can generate a new potential in the post-synaptic neuron.

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