One aspirin pill contains 360 mg of aspirin. To form 10 pills of aspirin from salicylic acid and acetic anhydride, how many grams of salicylic acid is required?

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Solution

Molar mass of salicylic acid = 138
Molar mass of aspirin = 180
10 pills of aspirin = 3600 mg of Aspirin = 3600/180 = 20 mmol of aspirin
Mass of salicylic acid required = 20 × 138 = 2760 mg = 2.76 gm of salicylic acid

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C_{7} H_{6} O_{3} + C_{4} H_{6} O_{3} \to C_{9} H_{8} O_{4} + C_{2} H_{4} O_{2}

C_{7} H_{6} O_{3} S a l i c y l i c a c i d (138.12 g m o l^{- 1}) + C_{4} H_{6} O_{3} A c e t i c a n h y d r i d e (102.09 g m o l^{- 1}) \to C_{9} H_{8} O_{4} A s p i r i n (180.15 g m o l^{- 1}) + C_{2} H_{4} O_{2} a c e t i c a c i d (60.05 g m o l^{- 1})

Write the chemical equation to convert salicylic acid to aspirin.

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