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Question

One histological sample of the mammary gland shows lobules scattered small ducts lined with cuboidal epithelium. In the second sample which was obtained at a different time from the same female, the lobules contained many more epithelial cells which were organized into alveoli as well as small ducts. When were the two samples most likely obtained?

A
during a normal menstrual cycle and during pregnancy
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B
before and after puberty
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C
before and after menopause
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D
during pregnancy and lactation
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Solution

The correct option is A during a normal menstrual cycle and during pregnancy
  • Each month, women go through changes in the hormones that make up the normal menstrual cycle.
  • The hormone estrogen is produced by the ovaries in the first half of the menstrual cycle. It stimulates the growth of milk ducts in the breasts. If pregnancy does not happen, the breasts go back to normal size.
  • The basic components of a mature mammary gland are the alveoli lined with milk-secreting cuboidal cells and surrounded by myoepithelial cells. These alveoli join to form groups known as lobules.
  • Each lobule has a lactiferous duct that drains into openings in the nipple. And changes occurs in the lobules of the alveoli. Hence, the mammary gland shows lobules scattered small ducts lined with cuboidal epithelium in the first sample. In the second sample which was obtained at a different time from the same female, the lobules contained many more epithelial cells which were organized into alveoli as well as small ducts.
So, the correct answer is 'during a normal menstrual cycle and during pregnancy'.

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