One of the following hormone is different from the other three regarding their solubility.

Epinephrine

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Aldosterone

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Steroid hormones

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Iodothyronines

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Solution

The correct option is D Epinephrine
Hormones can be classified based on their solubility into hydrophilic and lipophilic hormones. Hydrophilic hormones are soluble in water. They are mostly amino-based proteins. Examples include epinephrine, norepinephrine, insulin. Lipophilic hormones are soluble in lipids. They are steroids and thyroxine. Examples includes aldosterone, steroid hormones, iodothyronines.
Thus, the correct answer is 'Epinephrine.'

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