Question

One of the reasons for diabetes mellitus is

• A. Undersecretion of insulin
• B. Undersecretion of thyroxine
• C. Undersecretion of oestrogen
• D. None of the above

Answer 1

Answer: (A)

Undersecretion of insulin

Diabetes mellitus occurs when there is increased levels of sugar in blood and this condition is called hyperglycaemia. This disorder is caused due to deficiency or low secretion of insulin hormone. Insulin is secreted from the β cells of islets of Langerhans of pancreas. Insulin acts on hepatocytes and adipocytes and increases the uptake of cellular glucose and its utilisation. This leads to movement of glucose to hepatocytes and adipocytes from the blood, thereby resulting in the decreased blood glucose levels. Hence, if insulin secretion is low, then blood glucose levels will be high leading to diabetes mellitus.

So, the correct answer is 'Under secretion of insulin'.