Question

Osteoporosis, an age-related disease of skeletal system, may occur due to the.

• A. Immune disorder affecting neuromuscular junction leading to fatigue
• B. High concentration of $C{a}^{++}$ and $N{a}^{+}$
• C. Decreased level of oestrogen
• D. Accumulation of uric acid leading to inflammation of joints

Answer 1

Answer: (C)

Decreased level of oestrogen

Osteoporosis is an age related disorder of skeletal system caused due to weakening of bones by decreased Ca++ and oestrogen levels. Osetrogen helps in decreasing the resorption of bone by decreasing osteoclastic activity. As the oestrogen levels decrease the osteoclastic activity increases and more ca++ is withdrawn into blood from bone resulting in osteoporosis.

So the correct option is C.