The correct option is
D IHGWe can clearly see that each combination of three alphabets are the consecutive alphabets in reverse order.
RST,DEF,UVW
Now the one that should replace the question mark should also be of the same kind so the probable answers from the given options are options B,D
Now, considering left side of : :, we get
T,S,R, which are the 20th,19th,18th letter of alphabets respectively
And,F,E,D are the 6th,5th,4th letter of alphabets respectively
So, 20−6=19−5=18−4=14
Now, considering right side of : :, we get
W,V,U, which are 23rd,22nd,21st letter of alphabets respectively.
And from the left side we know that alphabets that replace question marks will be alphabets corresponding to following numbers,
23−14=9=I
22−14=8=H
21−14=7=G
Hence, the answer is IHG which is option D