Question

Oxidative decarboxylation occurs during the reaction

• A. Citrate Isocitrate
• B. Pyruvic acid Acetyl CoA
• C. Succinate Fumarate
• D. Fumarate Malate

Answer 1

The correct option is B Pyruvic acid Acetyl CoA

Pyruvic acid from glycolysis can only enter Krebs' cycle by going through a link reaction. In this, pyruvic acid is dehydrogenated and decarboxylated by the pyruvate dehydrogenase enzyme, liberating CO2 and H2. H2 reduces NAD to NADH2. The product formed is acetyl CoA. Such a reaction is called oxidative decarboxylation.

So the answer is 'Pyruvic acid Acetyl CoA'.