Question

Oxidative decarboxylation of pyruvic acid results in the formation of
I. Acetyl Co-A
II. $C{O}_2$
III. ATP
IV. $NADH+H^{+}$
Select the correct answer using the codes given below

• A. Only I
• B. I and II
• C. I, II and III
• D. I, II and IV
• E. III and IV

Answer 1

The correct option is D I, II and IV

In mitochondria, pyruvic acid (formed during glycolysis in cytosol) undergoes oxidative decarboxylation, i.e. removal of $C{O}_2$ in aerobic conditions.
The enzyme pyruvic acid dehydrogenase, found in the mitochondrial matrix, catlyses this reaction and results in the formation of a key compound, i.e. acetyl CoA.
Besides acetyl Co-A, $C{O}_2$ and $NADH+H^{+}$ are also formed by this process.