12. state the principle of process of centrifugation. List any three applications of centrifugation.
Centrifugation is a process which uses the power of centrifugal force for separation of substances based on densities, rotor speed, weight etc. When rotated at high speeds particles utilize centrifugal force instead of gravitational and separate on the basis of even tiny differences in gravity.
Applications:
A centrifuge is used to separate particles, cellular components, macro molecules, proteins and nucleic acids on the basis of density. It is also used to separate substances floating or present in a material.