Question

$P_{450}$ and $P_{448}$ occurs over

• A. S.E.R.
• B. R.E.R.
• C. Annulate E.R.
• D. Transitional E.R.

Answer 1

The correct option is A S.E.R.

• Cytochrome is proteins with heme as a cofactor.
• Cytochrome P450 and P448 contain enzymes which help in the detoxification and removal of carcinogenic compounds from the body.
  
• Cytochrome P450 and P448 (mainly in the liver cells) are located on the smooth endoplasmic reticulum (lipid synthesis and detoxification) and the few other cytochromes are located in the cristae of mitochondria (electron transfer).
• So, the correct answer is 'S.E.R'.