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Question

How has recombinant technology allowed the production of vaccines on a large scale?

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Solution

Vaccines are the biological preparations that are administered in the body to fight against a particular diseases. These usually consist of the parts of the pathogens in weakened state.

The recombinant technology has played a vital role in the production of vaccines, the vaccines produced by this technology are called as recombinant vaccines or subunit vaccines.

These vaccines are of two types:

a. Recombinant protein vaccines : When a pathogen attacks the body it will produce the proteins needed for the infection to occur. So the gene that encodes these proteins are extracted from the causative organism and are then used to develop the recombinant DNA. These recombinant DNA are then expressed in host organisms and are allowed to produce the particular protein. These proteins are then removed and purified and then injected into the body so that the body is able to produce immunogenic response to the disease and protect the organism in future.

b.DNA vaccines: These are the vaccines in which the DNA is used as the vaccines .

The recombinant technology is useful because here the actual pathogens will not be involved in vaccine production .

It is able to induce cellular and humoral responses as a result the vaccination will be effective.


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