Jaundice is a medical condition that occurs in almost all liver disorders like hepatitis, cirrhosis, bile duct blockage etc. It occurs by toxins, bacteria, virus etc. It is characterised by yellow colour of the skin, the mucous membranes, eyes etc due to high levels of the chemical bilirubin in blood.
Since, jaundice occurs by various agents, so it may occurs again and again. However, jaundice that occurs by virus like in hepatitis occurs only one time. Once a person recovers from Hepatitis, he develops antibodies that protect him from the virus for life.