Question

Since DNA is a hydrophilic molecule, it cannot pass through cell membranes.Why

Answer 1

DNA is present in the nucleus not in the cytoplasm just to protect them from various enzymes in the cytoplasm which make it difficult to reach the cell membrane to pass through it. Also DNA is a hydrophilic molecules cannot easily pass through the cell membranes, unlike hydrophobic molecules. Cell membrane is made up of phospholipids and cholesterols which makes the DNA (hydrophilic molecule) molecule impermeable.