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Question

1. In a certain population, the frequency of three genotypes is as follows:

Genotypes: BB Bb bb

frequency: 22% 62% 16%

What is the likely frequency of B and b alleles?

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Solution

According to hardy weinberg principle p2+2pq+q2

Thus, BB= p2, bb= q2

Frequency of B = All of BB + ½ of Bb = 22 +31 = 53%
Frequency of b = All of bb + ½ of Bb = 16 + 31 = 47%

Hardy Weinberg equilibrium is represented by

P 2 + q 2 + 2Pq = 1

Where, P 2 is the frequency of AA genotype individuals, q 2 is the frequency of aa genotype individuals Pq is the frequency of Aa genotype individuals.

Here, in this case, p2 = BB, q2 = bb, pq= Bb.

Therefore, frequency of B is likely to be 53% and that of b is likely to be 47%


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