298
Question
What could be the mechanism of uptake of the DNA of Type III S strain bacteria by Type II R strain bacteria?
What could be the mechanism of uptake of the DNA of Type III S strain bacteria by Type II R strain bacteria?
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Solution
The "transforming principle" given by Griffith revealed that the III-S strain bacteria had been killed. But the DNA had survived the heating process and was taken up by the II-R strain bacteria.
More to know:
O. T. Avery, McCleod and McCarty repeated the experiments of Griffith and found that when living R cells were mixed with the capsule of heat killed S type and infected into mice, there was no disease.
They injected R cells and the chromosome of S-bacteria mixture into mice. The mice developed pneumonia and died. They concluded that the chromosome of S-bacteria causes the transformation and not the capsule.
The "transforming principle" given by Griffith revealed that the III-S strain bacteria had been killed. But the DNA had survived the heating process and was taken up by the II-R strain bacteria.
More to know:
O. T. Avery, McCleod and McCarty repeated the experiments of Griffith and found that when living R cells were mixed with the capsule of heat killed S type and infected into mice, there was no disease.
They injected R cells and the chromosome of S-bacteria mixture into mice. The mice developed pneumonia and died. They concluded that the chromosome of S-bacteria causes the transformation and not the capsule.
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