Question

what is the significance of ampullary isthmic junction in female reproductive tract

Answer 1

After copulation, sperms travel through the cervix and finally reach the ampullary- isthmic junction of fallopian tube. Ovum after its release from ovary also travel to this place. If both ovum and sperms reach in the ampullary- isthmic junction at the same time, there is a strong chance of occurring fertilisation. So this junction may be considered as a site of fertilisation in human females.