The inferior vena cava is the large vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart. This vein ascends through the abdomen, collects blood from the hepatic veins, lumbar veins, gonadal veins, renal veins, and phrenic veins. The inferior vena cava enters the heart through the right atrium.
If there is a clot in this vein, there will be disruption in the flow of blood from these regions to the right atrium. The person will have painful lower limb swelling combined with lower back pain, pyrexia, dilatation of cutaneous abdominal wall veins.