1
Question
why is it not possible for an alien dna to become part of chromosome anywhere along its length and replicate normally?
why is it not possible for an alien dna to become part of chromosome anywhere along its length and replicate normally?
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Solution
It is not possible for an alien DNA to become part of chromosome anywhere along its length and replicate normally
because:
1. Alien DNA requires specific sequence called recognition sites (sites where restriction enzymes cut DNA) to ligate itself with host chromosome.
2. Also this sequence should be close to the origin of replication (Ori). It is the sequence where DNA replication starts. This site is necessary for the binding of DNA polymerase to start replication. As this site may not be present in all alien DNA molecules, so an alien piece of DNA cannot replicate normally by attaching to any DNA.
because:
1. Alien DNA requires specific sequence called recognition sites (sites where restriction enzymes cut DNA) to ligate itself with host chromosome.
2. Also this sequence should be close to the origin of replication (Ori). It is the sequence where DNA replication starts. This site is necessary for the binding of DNA polymerase to start replication. As this site may not be present in all alien DNA molecules, so an alien piece of DNA cannot replicate normally by attaching to any DNA.
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