why is it so that with every antigen, there is a corresponding antibody ? then how is it that AB blood group has no antibody and O blood group has no antigen?
With every antigen there is a specific antibody which can recognize the antigen and destroys it. There are several other antibodies also present whose corresponding antigens may not present in the body at this point of time but whenever these antigens enter the body, the antibodies recognize them promptly and start the encounter. The presence of antibodies and antigens in red blood cells (RBCs) which determine blood group is totally dependent upon the genes that regulate the specific protein synthesis. A person with AB blood group do not have A or B antibody and O blood group do not have A or B antigen due to the absence of specific genes that regulate their synthesis. But all other antibodies and antigens are present there.