why is thalassemia categorized as mendelian disorder. state the condition when an individual will suffer from the disease?
why is thalassemia categorized as mendelian disorder. state the condition when an individual will suffer from the disease?
Mendelian disorders are mainly determined by alteration or mutation in the single gene. Mendelian disorders can be traced in a family by the pedigree analysis. Mendelian disorders may be dominant or recessive. Thalassemia occurs by the mutation in the genes that make haemoglobin present in the red blood cells. It is an inherited autosomal recessive blood disorder . It leads to the weakening and destruction of red blood cells. It involves formation of abnormal form of hemoglobin, the protein in red blood cells that carries oxygen.
Patients of thalassemia suffer from anaemia, iron overload, bone deformities and cardiovascular illness,etc. Patients with severe thalassemia require repetitive blood transfusion.
Mendelian disorders are mainly determined by alteration or mutation in the single gene. Mendelian disorders can be traced in a family by the pedigree analysis. Mendelian disorders may be dominant or recessive. Thalassemia occurs by the mutation in the genes that make haemoglobin present in the red blood cells. It is an inherited autosomal recessive blood disorder . It leads to the weakening and destruction of red blood cells. It involves formation of abnormal form of hemoglobin, the protein in red blood cells that carries oxygen.
Patients of thalassemia suffer from anaemia, iron overload, bone deformities and cardiovascular illness,etc. Patients with severe thalassemia require repetitive blood transfusion.
