Paget’s disease is caused by

Prolonged deficiency of vitamin D in adults

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Abnormal bone resorption

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Excess of alkaline phosphatase

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Excess production and abnormal segregation of collagen

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Solution

The correct option is B Abnormal bone resorption
Paget's disease is caused by the excessive breakdown and formation of bone, followed by disorganized bone remodeling. This causes affected bone to weaken, resulting in pain, misshapen bones, fractures and arthritis in the joints near the affected bones.

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Similar questions

Fill in the blanks:

(a) _________ is caused by the deficiency of vitamin D.

(b) Deficiency of _________ causes a disease known as beri-beri.

(d) Night blindness is caused due to deficiency of _________ in our food.

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