Question

Periodic appearance of malaria symptoms occurs due to periodic

• A. Entry of merozoites into erythrocytes
• B. Attack of liver cells by merozoites
• C. Formation of signet ring
• D. Release of pyrogen in blood

Answer 1

Answer: (D)

Release of pyrogen in blood

Pyrogens are substances that cause a rise in blood temperature. These are released by the body in response to the pathogen or any pathogenic component present in the blood. A pyrogenic response is basically to eliminate the pathogenic components. In the case of malaria, fever is associated with rupture of intra-erythrocytic schizonts and release of the merozoites. These merozoites enters circulation and invades other red blood cells. Thus the correct answer is option D.