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Question

Pernicious anaemia, failure of erythrocytes to mature is mainly due to lack of

A
Vitamin K.
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B
Thiamine.
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C
Pyridoxine.
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D
Cyanocobalamin.
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Solution

The correct option is D Cyanocobalamin.
Cyanocobalamin or vitamin B12, is a substance having haematopoietic activity found in liver, fish meal, eggs, and other natural sources, or produced from cultures of Streptomyces griseus; it combines with intrinsic factor for absorption and is needed for erythrocyte maturation. Absence of intrinsic factor leads to malabsorption of cyanocobalamin and results in pernicious anaemia.

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