Question

Pernicious anaemia failure of erythrocytes to mature is mainly due to lack of

• A. Vitamin K
• B. Thiamine
• C. Pyridoxine
• D. Cyanocobalamin

Answer 1

The correct option is D Cyanocobalamin

Pernicious anemia is a condition caused by too little vitamin B${}_{12}$ in the body. It is a form of vitamin B${}_{12}$ deficiency anemia. Vitamin B${}_{12}$ helps the body make healthy red blood cells and helps keep nerve cells healthy. It is found in animal foods, including meat, fish, eggs, milk, and other dairy products. The most common cause of pernicious anemia is the loss of stomach cells that make intrinsic factor. Intrinsic factor helps the body absorb vitamin B${}_{12}$ in the intestine. The loss of parietal cells may be due to destruction by the body's own immune system. Pernicious anemia can cause permanent damage to nerves and other organs if it goes on for a long time without being treated. It also raises the risk for developing stomach cancer.

Therefore, the correct answer is option D.