Question

Phenotypically, females having rudimentary ovaries, underdeveloped breasts, short stature, webbed neck, often with subnormal intelligence suggest:

• A. Down’s syndrome
• B. Klinefelter’s syndrome
• C. Turner’s syndrome
• D. Haemophilic syndrome

Answer 1

The correct option is C Turner’s syndrome

In Turner’s syndrome, females have rudimentary ovaries, underdeveloped breasts, short stature, webbed neck, often with subnormal intelligence due to the absence of one of the X
chromosomes, i.e., (45, X0) chromosomal constitution.

Down’s syndrome is caused due to the presence of an additional copy of the chromosome number 21 (trisomy of 21). The affected individual is short statured with small round head, furrowed tongue and partially open mouth. Palm is broad with characteristic palm crease. Physical, psychomotor and mental developments are retarded.

Klinefelter’s syndrome is caused due to the presence of an additional copy of X-chromosome in males, resulting into a karyotype of 47, XXY. Such an individual has overall masculine development, however, the feminine development is also expressed. They are sterile.

Haemophilia is a sex-linked recessive disease in which a single protein that is a part of the cascade of proteins involved in the clotting of blood is affected. Due to this, in an affected individual, a simple cut will result in non-stop bleeding.