Question

Phosphorylation of glucose during glycolysis is catalyzed by

• A. Phosphoglucomutase
• B. Phosphoglucoisomerase
• C. Hexokinase
• D. Phosphorylase

Answer 1

The correct option is C

Hexokinase

The correct option is C.

The explanation for the correct option:

1. Glycolysis is a metabolic process that is the initial step for both aerobic and anaerobic cellular respiration.
2. In this glucose is converted into pyruvate.
3. In the first step of glycolysis, the conversion of glucose into glucose 6-phosphate takes place.
4. The enzyme that catalyzes this reaction is hexokinase.

The explanation for the incorrect options:
Option A

Phosphoglucomutase transfers the phosphate group to a D-glucose.
Option B
Phosphoglucoisomerase converts glucose 6-phosphate into its isomer fructose 6-phosphate.
Option D

Phosphorylase catalyses the addition of phosphate PO_4^- group from inorganic phosphate to an acceptor.

Final answer: Phosphorylation of glucose during glycolysis is catalyzed by hexokinase.