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Tobacco and nicotine causes oral cancer which can be life-threatening
Korsakoff's syndrome is a disorder in which memory deficits are disproportionate to other cognitive deficits. It is a form of amnesia which is primarily caused by thiamine depletion that is usually associated with chronic alcoholism, but also occasionally with malnutrition.
Laennec syndrome can cause Cirrhosis in itself is already a late stage of liver damage. In the early stages of liver disease there will be inflammation of the liver.
Wernicke's encephalopathy appears suddenly and is characterized by ophthalmoplegia and ataxia followed by mental disturbance. The ocular disturbance, which is necessary for the diagnosis, consists of paresis or paralysis of the lateral rectus muscles, nystagmus, and a disturbance in conjugate gaze.
Mallory-Weiss syndrome is characterized by upper gastrointestinal bleeding secondary to longitudinal mucosal lacerations (known as Mallory-Weiss tears) at the gastroesophageal junction

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