............... plays a crucial role in detoxifying many poisons and drugs in a cell.

Golgi apparatus

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Lysosome

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Smooth endoplasmic reticulum

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Vacuole

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Solution

The correct option is C Smooth endoplasmic reticulum
The smooth endoplasmic reticulum (SER) is a type of endoplasmic reticulum that does not have ribosomes. Hence, the name smooth endoplasmic reticulum. It plays an important role in the production of lipids that are important for the cell. SER also helps in the detoxification of many poisons and drugs within the liver cells of vertebrates.
So, the correct answer is option C.

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