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Question

Pleiotropic gene

A
Controls only one phenotype
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B
Controls several phenotypes
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C
Masks the expression of another non-allelic gene
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D
Inhibits cross over
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E
Promotes crossing over
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Solution

The correct option is A. Controls several phenotypes.
Pleiotropic gene: A gene that affects more than one phenotype. Pleiotropy results in different expressions at the phenotypic level.

For example, sickle cell anaemia and cystic fibrosis in men. Pleiotropy occurs when one gene influences multiple, seemingly unrelated phenotypic traits, an example being phenylketonuria, which is a human disease that affects multiple systems but is caused by one gene defect.

Consequently, a mutation in a pleiotropic gene may have an effect on some or all traits simultaneously. Pleiotropic gene action can limit the rate of multivariate evolution when natural selection, sexual selection or artificial selection on one trait favours one specific version of the gene, while selection on the other traits favours a different allele.


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