Polymerisation of DNA is in

3^{'} \to 5^{'}

direction

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5^{'} \to 3^{'}

direction

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Both

3^{'} \to 5^{'}

and

5^{'} \to 3^{'}

direction

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None of the above

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Solution

The correct option is D $5^{'} \to 3^{'}$ direction
DNA polymerase has 5' $\to$ 3' activity. All known DNA replication systems require a free 3' hydroxyl group before synthesis can be initiated (note: the DNA temple is read in 3' to 5' direction whereas a new strand is synthesized in 5' to 3' direction).
So, the correct answer is "5' $\to$ 3' ".

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Similar questions

Q. Assertion :Synthesis of daughter or new strand occurs continuously along the parent 3

\to

5 strand. Reason: DNA polymerase can polymerise nucleotides in 3

\to

5 direction on 5

\to

3 strand.

Q. In DNA, if one of the strands' direction is 5-3, the direction of the other strand is:

If the sequence of one strand of DNA is written as follows
5' - ATGCATGCATGCATGCATGCATGCATGC - 3'
Write down the sequence of complementary strand in 5' $\to$ 3' direction.

Q. Why does synthesis of DNA proceed only in the

5^{'}

3^{'}

direction?

Q. Why replication is not continuous on the DNA template with

5^{'} \to 3^{'}

direction?

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