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Question

Polysome is formed by

A
A ribosome with several subunits
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B
Ribosomes attached to each other in a linear arrangement
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C
Several ribosomes attached to a single mRNA
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D
Many ribosomes attached to a strand of endoplasmic reticulum
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Solution

The correct option is C Several ribosomes attached to a single mRNA
Polyribosomes (or polysomes) are a cluster of ribosomes, bound to an mRNA molecule. Polysomes are functional unit of protein synthesis. The synthesis of proteins starts with the binding of the ribosome on the rough endoplasmic reticulum at the translocon. A ribosome only binds to the RER once a specific protein-nucleic acid complex is formed in the cytosol. This special complex forms when a free ribosome begins translating the mRNA of a protein destined for the secretory pathway. The first 5-30 amino acids polymerized encode a signal peptide, a molecular message that is recognized and bound by a signal recognition particle.

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