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Question

Predict the product of the following reaction and choose the correct options.


A

It is a named reaction called the Wharton reaction

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B

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C

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D

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Solution

The correct options are
A

It is a named reaction called the Wharton reaction


C


It is a named reaction called the Wharton reaction. It is a variation of the Wolff-Kishner:
First step is the formation of the hydrazone;

Now, a base - say acetate ion - abstracts the proton from the nitrogen:


Once again, the base abstracts a proton but this time, it results in the opening of the epoxide ring:


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