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Question

Product formed by the activity of malic dehydrogenase in the TCA cycle is

Fumaric acid.

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Malic acid.

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Oxaloacetic acid.

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Succinic acid.

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Solution

The correct option is C Oxaloacetic acid.
Malic acid dehydrogenase or malate dehydrogenase is a Krebs cycle enzyme, which converts malic acid into oxaloacetic acid with the simultaneous reduction of one NAD molecule into reduced coenzyme $N A D H_{2}$ .

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C O_{2}

\begin{matrix} I . C i t r i c a c i d & \to & α - k e t o g l u t a r i c a c i d I I . S u c c i n i c a c i d & \to & M a l i c a c i d I I I . M a l i c a c i d & \to & O x a l o a c e t i c a c i d I V . α - k e t o g l u t a r i c a c i d & \to & S u c c i n y l C o - A \end{matrix}

^{+}

\to

\to

\to

\to

N A D^{+}

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