Question

Proliferation of endometrium of uterus in proliferative phase is controlled by

• A. Relaxin
• B. Oxytocin
• C. Progesterone
• D. Oestrogen
• E. Luteinizing hormone

Answer 1

Answer: (D)

Oestrogen

Within the developing follicles, theca interna cells secrete androgens, which are converted into estrogen by the granulosa cells of the follicles. This conversion is stimulated by LH.

Estradiol or estrogen causes endometrial proliferation, as well as development of the glands and growth of spiral arteries within the endometrium, in preparation for possible implantation of a fertilized egg. So, the estrogens initiate the formation of a new layer of endometrium in the uterus, histologically identified as proliferative endometrium.

So, the correct answer is 'Oestrogen'