Pyruvate dehydrogenase activity during aerobic respiration requires:

Calcium

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Iron

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Cobalt

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Magnesium

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Solution

The correct option is D Magnesium
Pyruvate is the end product of glycolysis.

Pyruvate enters mitochondria from the cytoplasm and undergoes oxidative decarboxylation to produce acetyl CoA, CO2 and NADH.

The reaction occurs in the presence of an enzyme complex pyruvate dehydrogenase (made up of a decarboxylase, lipoic acid, TPP, transacetylase and Mg²⁺).

Therefore, option d is correct as pyruvate dehydrogenase activity during aerobic respiration requires magnesium.

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