Question

Q15. Consider the following statements

1. The pyrogen test is carried out to check impurity or substance that can cause adverse side-effects.

2. The abnormal toxicity test is carried out to check potential hazardous biological contamination in vaccine formulations.

Which of the above are statements are correct?

• A. a) 1 only
• B. b) 2 only
• C. c) Both 1 and 2
• D. d) None of the above

Answer 1

The correct option is C

c) Both 1 and 2

Pyrogen test

The pyrogen test is carried out to check impurity or substance that can cause adverse side-effects. For the test, the drug is injected into a rabbit and the animal is closely observed for feverish symptoms.

Abnormal toxicity test

The abnormal toxicity test is carried out to check potential hazardous biological contamination in vaccine formulations