Question 57
Differentiate between rough and smooth endoplasmic reticulum. How is the endoplasmic reticulum important for membrane biogenesis?
Question 57
Differentiate between rough and smooth endoplasmic reticulum. How is the endoplasmic reticulum important for membrane biogenesis?
The endoplasmic reticulum is a network of membranes found throughout the cell and connected to the nucleus. Rough ER (RER) is involved in protein production, protein folding, quality control and despatch. It is called ‘rough’ because it is studded with ribosomes.
Smooth ER (SER) is associated with the production and metabolism of fats and steroid hormones. It is ‘smooth’ because it is not studded with the ribosomes and is associated with smooth slippery fats.
The SER helps in the manufacture of fat molecules or lipids important for cell function.
Since the cell membrane is in a constant state of flux with endosmosis and exosmosis happening both at the same time including active transport, it undergoes a lot of wear and tear. These sites of tear need to be repaired immediately. The proteins and lipids help in rebuilding the cell membrane.This process of cell membrane repair is known as membrane biogenesis.
The endoplasmic reticulum is a network of membranes found throughout the cell and connected to the nucleus. Rough ER (RER) is involved in protein production, protein folding, quality control and despatch. It is called ‘rough’ because it is studded with ribosomes.
Smooth ER (SER) is associated with the production and metabolism of fats and steroid hormones. It is ‘smooth’ because it is not studded with the ribosomes and is associated with smooth slippery fats.
The SER helps in the manufacture of fat molecules or lipids important for cell function.
Since the cell membrane is in a constant state of flux with endosmosis and exosmosis happening both at the same time including active transport, it undergoes a lot of wear and tear. These sites of tear need to be repaired immediately. The proteins and lipids help in rebuilding the cell membrane.This process of cell membrane repair is known as membrane biogenesis.
