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Question

Raju is suspected of facing a major deficiency of antibodies. To confirm the same, which component needs to be looked for confirmatory evidence?


A
Serum globulins
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B
Serum Albumins
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C
Fibrinogen in plasma
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D
Haemocytes
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Solution

The correct option is A Serum globulins

When an individual is suspected of immunodeficiency, their health-care provider suggests measuring immunoglobulins to diagnose IgG deficiency i.e. serum globulin test.

Lower serum albumin indicates that the person is malnourished, or has liver diseases such as cirrhosis or chronic hepatitis. Higher albumin level is caused by acute infections, burns and stress.

Fibrinogen in plasma helps in creating blood clots; low level of fibrinogen is related to the body's inability to produce fibrinogen due to acquired conditions such as end-stage liver disorder or severe malnutrition.

Haemocytes are the effector cells of the immune system that participate in various cellular defences such as phagocytosis, encapsulation, and clotting in invertebrates. In addition, they mediate systemic immune responses and are actively involved in antimicrobial peptide synthesis.


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