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Question

Rate limiting step in glycolysis is

A
Glucose to glucose 6-phosphate
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B
Fructose 6- phosphate to fructose 1,6-diphosphate
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C
Glyceraldehydde -3 phosphate to 3-phosphoglyceric acid
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D
Both A and B
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Solution

The correct option is C Both A and B
The rate limiting steps of a metabolic pathway are that reaction which regulates the pathway by feedback mechanism. The rate limiting steps in the glycolytic pathway are:
(i) The phosphorylation of glucose by hexokinase or glucokinase.
(ii) The phosphorylation of fructose-6-phosphate to form fructose-1,6-bisphosphate by fructose-6-phosphate kinase.
(iii) The conversion of phosphoenolpyruvate to pyruvate by pyruvate kinase.
Thus, the correct answer is option D.

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