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Question

Read the following statement and inferences, and select the correct option.

Statement: The core of the larger ribosomal subunit, where the transfer of the peptidyl bonds happen from one amino acid to the next, is made up entirely of rRNA

Inference:

A.      rRNA is smaller than proteins and hence can fit in the smallest of crevices

B.      rRNA has catalytic capability and hence confers the name ribozyme to ribosome

C.      rRNA has higher binding affinity with each other and hence excludes proteins from its core structure

D.      The proteins which make up ribosome do not have a significant role to play in its catalytic activity

Which of the inferences are true?
  1. B and C only
  2. D only
  3. A only
  4. All of the above


Solution

The correct option is D All of the above
Ribosomes are made up of rRNA and proteins. The proteins present in ribosomes act only as structural scaffolding. The real player behind the scenes is rRNA especially in the larger subunit. rRNA is quite smaller than proteins and since it also has more affinity toward each other, they bind closely together and form the structural core. Due to the inherent ability of RNA to catalyse reactions of itself and other molecules, the rRNA core forms the catalytic core too where it catalyses the transfer of peptidyl bonds between the incoming amino acids.

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