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Question

Read the following statement having two blanks A and B.
In ”____A____, ____B____” an American Company prepared two DNA sequences corresponding to A and B chains of human insulin and introduced them in plasmids of Escherichia coli to produce insulin chains.”
Identify the correct option for the two blanks.

A
A - 1983 , B - Eli Lilly
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B
A - 1982, B - Eli Lily
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C
A - 1985, B - Eli Lilly
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D
A - 1986, B - Eli Lily
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Solution

The correct option is A A - 1983 , B - Eli Lilly
In 1983, Eli Lilly, an American company prepared two DNA sequences corresponding to A and B chains of human insulin and introduced them in plasmids of Escherichia coli to produce insulin chains. Chains A and B were produced separately, extracted and combined by creating disulphide bonds to form human insulin. In 1986, Eli Lilly company received approval to market human insulin under the trade name Humulin.

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