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Question

Read the following statements and find out the incorrect statement(s).

a. The binding of CO2 with haemoglobin is related to the partial pressure of CO2.pO2 is a major factor which could affect this binding.

b. When pCO2 is low and pO2 is high as in the alveoli, more binding of CO2 occurs, whereas when the pCO2 is high and pO2 is low as in the tissues, dissolution of CO2 from carbaminohaemoglobin takes place.

c. At the tissue site, where partial pressure of CO2 is high due to catabolism, CO2 diffuses into blood (RBCsand plasma) and forms HCO−3 and H+. At the alveolar site where pCO2 is low, the reaction proceeds in the opposite direction leading to the formation of CO2 and H2O.

d. Oxygen dissociation curve is highly useful in studying the effect of factor like pCO2,H+ concentration, etc., on binding of O2 with haemoglobin.


A
c and d
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B
b only
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C
a and b
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D
b and c
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Solution

The correct option is B b only

Statement b

When pCO2 is low and pO2 is high as in the alveoli, more binding of CO2 occurs, whereas when the pCO2 is high and pO2 is low as in the tissues, dissolution of CO2 from carbaminohaemoglobin takes place.

Elaboration

The partial pressures of O2 and CO2 play a major role in binding of these gases with haemoglobin. In the alveoli, the partial pressure of O2is higher than that of CO2. This causes the dissociation of CO2 from the carbaminohaemoglobin.

Hence this statement is incorrect.

Final Answer:

D only


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