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Mechanism of Enzyme Action

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Question

Read the statements given below and mark the correct option.

A

Apoenzymes are non- proteinaceous prosthetic groups

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B

Bell- shaped curve is obtained when enzyme activity is plotted against factors such pH & temperature

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C

Specificity of enzyme action is a property of tertiary structure of proteins usually

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D

Enzymes increase rate of reaction by altering the equilibrium of reaction

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Solution

The correct option is B Bell- shaped curve is obtained when enzyme activity is plotted against factors such pH & temperature
A change in pH of enzyme catalyzed reaction markedly affects its velocity and bell shaped curve is obtained if enzyme activity is plotted against factors such as pH and temperature.

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Q. Assertion :A coenzyme or metal ion tightly bound to enzyme protein is called prosthetic group. Reason: A complete catalytically active enzyme together with its bound prosthetic group is called apoenzyme.

Q. Assertion :A coenzyme or metal ion that is very tightly bound to enzyme protein called prosthetic group. Reason: A complete, catalytically active enzyme together with its bound prosthetic group is called apoenzyme.

Q. Assertion (A): A coenzyme or metal ion that is very tightly bound to enzyme protein is called prosthetic group.
Reason (R): A complete catalytically active enzyme together with its bound prosthetic group is called apoenzyme.

Q. Consider the following statements:
(A) Co-enzyme or metal ion that is tightly bound to enzyme protein is called prosthetic group
(B) A complete catalytic active enzyme with its bound prosthetic group is called apoenzyme.

Select the correct option.

Q. Complete the following passage(s) with an appropriate word/term to be filled in the blank spaces.
Apoenenzyme, Polypeptide, Prosthetic, Co-enzyme, Cofactors
Enzymes are composed of one or several .......... (1) ........ chains. However, there are a number of cases in which non-protein constituents called ........(2)........ are bound to the the enzyme to make the enzyme catalytically active. In these instances, the protein portion of the enzymes is called the ..........(3)......... Three kinds of cofactors may be identified prosthetic groups, co-enzymes and metal ions. ..........(4).......... groups are organic compounds and are distinguished from other cofactors in that they are tightly bound to the apoenzyme. For example, in peroxidase and catalase, which catalyze the breakdown of hydrogen peroxide to water and oxygen, haem is the prosthetic group and it is a part of the active site of the enzyme. .......(5)......... are also organic compounds but their association with the apoenzyme is only transient, usually occurring during the course of catalysis, Furthermore co-enzymes serve as co-factors in a number of different enzyme catalyzed reactions. The essential chemical components of many coenzymes are vitamins, e.g., coenzyme nicotinamide adenine dinucleotide (NAD) and NADP contain the vitamin niacin.

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