Question

Rearrange the sequential order as formed during the breakdown of glucose into pyruvate.

Glucose 6-phosphate, Fructose 6-phosphate, PGA, Pyruvate

• A. Glucose 6 phosphate $\to$ Fructose 6 phosphate $\to$ PGA $\to$ Pyruvate
  
• B. Pyruvate $\to$ Glucose 6 phosphate $\to$ Fructose 6 phosphate $\to$ PGA
• C. Pyruvate $\to$ Fructose 6 phosphate $\to$ Glucose 6 phosphate $\to$ PGA
• D. Glucose 6 phosphate $\to$ PGA $\to$ Fructose 6 phosphate $\to$ Pyruvate

Answer 1

The correct option is A Glucose 6 phosphate $\to$ Fructose 6 phosphate $\to$ PGA $\to$ Pyruvate

Glycolysis is the metabolic pathway that converts glucose into pyruvate. There are 10 steps involved in the process of glycolysis. First, the glucose is broken down into glucose-6-phosphate in presence of enzyme hexokinase. Glucose-6-phosphate is then converted into fructose-6-phosphate by the enzyme isomerase. Fructose-6-phosphate is then converted into fructose-1,6-biphosphate by enzyme phosphofructokinase. This fructose-1,6-biphosphate is then broken down into dihydroxyacetone phosphate and glyis then converted into 1,3-bisphosphoglyceric acid by enzyme dehydrogenase. A 1,3-bisphosphoglyceric acid is then converted into 3-phosphoglyceric acid by enzyme kinase. A 3-sphosphoglyceric acid is converted into 2-phosphoglyceric acid by enzyme mutase. A 2-phosphoglyceric acid is converted into phosphoenolpyruvic acid by enzyme enolase. This phosphoenolpyruvic acid then forms pyruvate by enzyme kinase.

Thus, the correct answer is 'Glucose 6 phosphate → Fructose 6 phosphate → PGA → Pyruvate.'